MACP BYPASS VARIANTS OF STREPTOCOCCUS PNEUMONIAE PBP2A SUGGEST A CONSERVED MECHANISM FOR THE ACTIVATION OF BIFUNCTIONAL CELL WALL SYNTHASES

MacP bypass variants of Streptococcus pneumoniae PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases

ABSTRACTThe peptidoglycan (PG) layer protects bacteria from osmotic lysis and defines their shape.The class A penicillin-binding proteins (aPBPs) are PG synthases that possess both glycan polymerization and crosslinking activities needed for PG biogenesis.In Gram-negative bacteria, aPBPs require activation by outer membrane lipoproteins, which are

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Perceptions on Diet and Dietary Modifications during Postpartum Period Aiming at Attenuating Progression of GDM to DM: A Qualitative Study of Mothers and Health Care Workers

Background.Gestational diabetes mellitus (GDM) is a global concern.GDM mothers have a 7-fold relative risk of developing type 2 diabetes mellitus (T2DM) in their later life.User-friendly and culturally acceptable dietary interventions can minimize this risk.Therefore, this study aims at exploring the perceptions of GDM mothers and health care worke

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